Introduction: Jim Welch and Caryl Griffin Section I. Hazard Identification, Editor: Dawn WooleyMicrobial Flora of Humans and Microbial Virulence Factors, Paul A. Granato, Lab. Alliance of Central NYIndigenous Agents of Research Animals, Lon Kendall, Colorado State U.Plant Pathogens and Plant-Associated Microorganisms, Ann K. Vidaver et al., U. NebraskaEpidemiology of Laboratory-Associated Infections, Karen Byers, Dana Farber Cancer Inst. Section II. Hazard Assessment, Editor: Dawn WooleyRisk Assessment of Biological Hazards, Dawn Wooley, Wright State U.Helminths, Protozoa, and Algae, Barbara L. Herwaldt, CDCMycotic Agents, Wiley A. Schell, Duke UniversityBacterial Pathogens, Deborah Anderson, U. MissouriViral Agents, Jason Paragas, Lawrence Livermore National Lab, Livermore, CAViral Vectors, Patrick J. Condreay, pc Biosafety Consulting Services, Carrboro, NCToxins of Biological Origin, Joseph P. Kozlovac, USDAMolecular Agents, Dawn Wooley, Wright State U.Biohazardous Agents Transmitted Primarily by the Airborne Route, Michael A. Pentella, Dept. Public Health, Bureau of Lab Science, Boston, MAPrimary, Continuous, and Transformed Cells, Glyn Stacey, National Inst of Biol Stand and ControlAllergens of Animal and Biological Systems, Wanda Phipatanakul, Children's Hosp. and Harvard Section III. Hazard Control, Editor: Dawn Wooley and Karen Byers Design of Biomedical Laboratory Facilities, Jonathan Y. Richmond Primary Barriers and Equipment-Associated Hazards, Richard C. Fink Biological Safety Cabinets, Fume Hoods, and Gloves Boxes, David C. Eagleson, The Baker Company Arthropod Vector Biocontainment, Stephen Higgs, Kansas State University, Manhattan, KS Aerobiology, Allen Bennett, Simon Parks, Clare Shieber Personal Respiratory Protection, Nicole Vars McCullough Universal Precautions for Handling Human Specimens, Debra L. Hunt Decontamination and Disinfection, Matthew J. Arduino, Centers for Disease Control, Atlanta, GA Packaging and Shipping Biological Materials, Ryan F. Relich and James W. Snyder Section IV. Administrative Control, Editor: Karen ByersBiological Safety Program Management, LouAnn Crawford Burnett, Chris Thompson, Patricia Olinger Biosafety Compliance: a Global Perspective (title may be changed slightly, but will be regarding international biorisk issues, Patricia Olinger and R KalpanaOccupational Medicine in a Biomedical Research Setting, Deborah E. Wilson and James M. SchmittMeasuring Biosafety Program Effectiveness, Janet S. Peterson (retired), Melissa Morland, Robert J. Hashimoto (deceased). Training Programs, Sean KaufmanBiosafety and Biosecurity: Regulatory Impact, Robert J. Hawley and Theresa D. Duley Section V. Special Environments, Editor: Karen ByersTeaching Laboratories, Christopher WoolvertonPharmaceutical Industry, Brian PetuchLarge-Scale Production, Mary L. Cipriano, Brian Petuch, and Marion Downing. Veterinary Diagnostic Laboratories and Necropsy, Timothy Baszler and Tanya GrahamAgricultural Biosafety, Robert A. Heckert and Joseph P. KozlovacLaboratory, Growth Chamber, and Greenhouse Biosafety, Dann Adair et al.Field Studies, Charles Calisher and Darrin CarrollClinical Settings, Michael A. PentellaBSL-4 Maximum Biocontainment Laboratories, David S. Bressler and Robert J. Hawley