✍ Scribed by Klaus Schwarz; Arne Fredga
No coin nor oath required. For personal study only.
The diselenides of straight-chain aliphatie alcohols with 2 to 4 carbon atoms, and the acetic acid ester of the CJ hcmolog were similar in powney to the corresponding carboxylic acids in protecting against dietary liver necrosis in the rat. As in carboxylic acids, substitution of a methyl group at the carbon atom adjacent to the selenium atom diminished activity, but a methyl group in the @ position had no such effect. Two methyl groups in the 6 position, producing a quaternary carbon atom, abolished biological activity, as seen in other series of compounds. D'&elenides of alipbatic and heterocyclic amines showed low biologicsl activity. SAminopmpyl diselenide was half 85 active and dimethyl and
📜 SIMILAR VOLUMES
Straight-chain aliphatic seleninic acids, CH3-(CH2)n-SeOOH, with chain lengths from C4 to C17, a few dibasic acids of moderate chain length having seleninic acid groups on both ends of the molecule, HOOSe-(CH2)n-SeOOH, and a series of carbosyseleninic acids, HOOC-R-SeOOH, comprising chain lengths fr
Several 2,4-dinitrophenylseleno-carboxylic acids, a number of unsubstituted and 4-substituted benzylselenocarboxylic acids, and some phenyletbylseleno-carboxylic acids have been investigated with regard to their potency in the prevention of dietary liver necrosis. The potency was strongly influenced
## Abstract ^77^Se NMR chemical shifts and ^1^__J__(SeC) coupling constants were measured for nine organic selenium compounds: 4,5,6,7‐tetrahydro‐,4′,4′,6,6‐tetramethylspiro[1,3‐benzoxaselenole‐2,1′‐cyclohexane]‐2′,4,6′‐trione and closely related derivatives, bis(2‐hydroxy‐4,4,6,6‐tetramethyl‐3‐oxo