Biological Performance of Materials : Fundamentals of Biocompatibility, Fourth Edition

✍ Scribed by Black, Jonathan

• Publisher: CRC Press
• Year: 2005
• Tongue: English
• Leaves: 520
• Edition: 4th ed
• Category: Library

✦ Synopsis

GENERAL CONSIDERATIONSBiocompatibility: Definitions and Issues Introduction Biological Performance Consensus Definitions Discussion The Discipline of Biomaterials Afterword: Paradigmatic Shift Introduction to the Biological Environment General Considerations Comparison of External and Internal ConditionsProblems in Definition of the Biological EnvironmentElements of the Biological Environment Implant Life History Preimplantation Handling Effects MATERIAL RESPONSE: FUNCTION ANDDEGRADATION OF MATERIALSIN VIVOSwelling and Leaching Introduction Fick's Laws of DiffusionAbsorption Examples of Undesi. Read more...

Abstract:

Focuses on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices. This book summarizes the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. Read more...

✦ Table of Contents

Content: Front cover
Preface
Abstract
The Author
Contents
Part I
General Considerations
Chapter 1
Biocompatibility: Definitions and Issues
1.1 Introduction
1.2 Biological Performance
1.3 Consensus Definitions
1.4 Discussion
1.5 The Discipline of Biomaterials
1.6 Afterword: Paradigmatic Shift
References
Bibliography
Chapter 2
Introduction to the Biological Environment
2.1 General Considerations
2.2 Comparison of External and Internal Conditions
2.3 Problems in Definition of the Biological Environment
2.4 Elements of the Biological Environment
2.5 Implant Life History 2.6 Preimplantation Handling EffectsReferences
Bibliography
Part II
Material Response: Function and Degradation of Materials In Vivo
Chapter 3
Swelling and Leaching
3.1 Introduction
3.2 Fick's Laws of Diffusion
3.3 Absorption
3.4 Examples of Undesirable Absorption
3.5 Osmotic Equilibrium
3.6 Leaching
3.7 Example of Planned Leaching: Drug Release
3.8 Effects of Swelling and Leaching
References
Bibliography
Chapter 4
Corrosion and Dissolution
4.1 Chemistry of Corrosion
4.2 Classification of Reactions
4.3 The Pourbaix Diagram
4.3.1 Reactions of Chromium in Pure Water 4.3.2 Reactions of Chromium in the Presence of Aqueous Chloride Ion4.4 The Electrochemical Series
4.4.1 Ideal Series
4.4.2 Practical Series
4.5 Corrosion Rate
4.6 Potential-Current Relationships in Corrosion
4.7 Forms of Corrosion
4.7.1 Uniform Attack
4.7.2 Galvanic Corrosion
4.7.3 Crevice Corrosion
4.7.4 Pitting Corrosion
4.7.5 Intergranular Corrosion
4.7.6 Leaching
4.7.7 Erosion Corrosion
4.7.8 Stress and Fatigue Corrosion
4.8 Corrosion in Implant Applications
4.9 Engineering Variables Affecting Corrosion Rates
4.10 Corrosion Factors Peculiar to Biological Environments 4.11 Ceramic Dissolution4.12 Polymer Dissolution
4.13 Final Remarks
References
Bibliography
Chapter 5
Reactions of Biological Molecules with Biomaterial Surfaces
5.1 Introduction
5.2 Denaturation
5.3 Organometallic Compounds
5.3.1 Definitions
5.3.2 Stability
5.3.3 Production
5.4 Mechanical Aspects of Interfaces
5.5 Results of Interfacial Adhesion of Molecules
5.6 Effects of Charged Interfaces and Ions
5.7 Final Comments
References
Bibliography
Chapter 6
Mechanics of Materials: Deformation and Failure
6.1 Introduction
6.2 Mechanics of Materials
6.3 Elastic Modulus 6.3.1 Fundamental Aspects6.3.2 Environmental Effects
6.4 Yield Strength
6.4.1 Fundamental Aspects
6.4.2 Environmental Effects
6.5 Fracture Strength
6.5.1 Fundamental Aspects
6.5.2 Environmental Effects
6.6 Final Comment
References
Bibliography
Chapter 7
Friction and Wear
7.1 Introduction
7.2 Friction
7.3 Lubrication
7.3.1 Hydrodynamic
7.3.2 Elastohydrodynamic
7.3.3 Squeeze Film
7.3.4 Boundary
7.3.5 Mixed
7.3.6 Types of Lubricant Behavior in Response to Shear
7.4 Wear
7.4.1 Introduction
7.4.2 The Transfer Film
7.4.3 Other Wear Mechanisms
7.4.4 Evidence of Wear In Vivo

✦ Subjects

Biocompatibility. Biomedical materials -- Testing. Biomedical materials.