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Biological markers of oxidative stress in mitochondrial myopathies with progressive external ophthalmoplegia

✍ Scribed by G. Piccolo; P. Banfi; G. Azan; R. Rizzuto; R. Bisson; D. Sandoná; G. Bellomo


Book ID
118931205
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
357 KB
Volume
105
Category
Article
ISSN
0022-510X

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We studied muscle fatigue and serum lactate and pyruvate levels in 20 patients with mitochondrial myopathy with progressive external ophthalmoplegia (PEO). Fatigue was assessed in the adductor pollicis muscle (AP) using a low-intensity exercise protocol (20 min). Forces (TFs) and relaxation times of