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Biological evaluation of glucose and deoxyglucose derivatives radiolabeled with [99mTc(CO)3(H2O)3]+ core as potential melanoma imaging agents

✍ Scribed by Rosina Dapueto; Romina Castelli; Marcelo Fernández; José A. Chabalgoity; María Moreno; Juan Pablo Gambini; Pablo Cabral; Williams Porcal

Book ID
113496230
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
361 KB
Volume
21
Category
Article
ISSN
0960-894X

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✍ Kristof Prinsen; Lixin Jin; Kathleen Vunckx; Marijke De Saint-Hubert; Lin Zhou; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 581 KB

N,N'-bis(diethylenetriamine pentaacetic acid)-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) (bis-DTPA-BI) was radiolabeled with (99m)Tc(CO)(3). The resulting (99m)Tc(CO)(3)-bis-DTPA-BI was characterized (LC-MS) and evaluated as a potential SPECT tracer for imaging of necrosis in Wistar rats wi