Biological effects of aminoguanidine: An update
✍ Scribed by B.-O. Nilsson
- Book ID
- 105753897
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1999
- Tongue
- English
- Weight
- 88 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
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Aminoguanidine is an inhibitor of nitric oxide synthase (NOS), with high selectivity for the inducible isoform (iNOS). In addition to being an inhibitor of NOS, aminoguanidine also exhibits antioxidant activity. Recent studies suggest that aminoguanidine reduces ischaemia-reperfusion (I/R)-induced d