Synthesis and biological activity of tac
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Daniela Pinzani; Anna Maria Papini; Mario Chelli; Mauro Ginanneschi; Carlo Alber
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Article
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1996
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Springer Netherlands
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English
โ 511 KB
2-adamantanole was the protecting group of the aspartate 13-COOH moiety during the peptide synthesis and survived the final peptide cleavage and deprotection carried out under controlled conditions. MEN 10586 showed an agonist activity comparable to that of the parent compound MEN 10210 at NK~ and N