Biological activities of chemically synthesized N-acetylneuraminic acid-(α2→6) -monosaccharide analogs of lipid A
✍ Scribed by Tadayori Shimizu; Toshiyuki Masuzawa; Yasutake Yanagihara; Chikako Shimizu; Kiyoshi Ikeda; Kazuo Achiwa
- Book ID
- 115920724
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 247 KB
- Volume
- 228
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Glycosidation of N-acetylneuraminic acid by phase-transfer catalysis in chloroform-aqueous alkali gave several known and some new aryl cY-ketosides in a short reaction time and in good yields. The 4-methylumbelliferyl cu-ketoside, the standard substrate for neuraminidase, was prepared in a yield of
Sialylated and fucosylated lactosaminyl structures such as sialyl Lewis', sialyl dimeric Lewis", and its internally monofucosylated derivative have been proposed as ligands for the E-and the P-selectins'-4. The availability of pure synthetic materials is critical for the evaluation of the binding sp