Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells
โ Scribed by Aguilar, Zuleima; Akita, Robert W; Finn, Richard S; Ramos, B Lillian; Pegram, Mark D; Kabbinavar, Fairooz F; Pietras, Richard J; Pisacane, Paul; Sliwkowski, Mark X; Slamon, Dennis J
- Book ID
- 110062384
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 351 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Recently, a family of growth factors has been described that activates erbB-2 receptors. These factors, known as the neu differentiation factors (NDF) or heregulins (HRG), induce tyrosine phosphorylation of erbB-2 receptors as a result of their direct interaction with either erbB-3 or erbB-4 recepto
Ovarian cancer arises mostly from the ovarian surface epithelium. The aim of our study was to compare the effects of cytokines in ovarian surface epithelial (OSE) cells and in ovarian carcinoma cells. Proliferation and expression of surface antigens (CA-I25 and classes I and II antigens of the major