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Biokinetics of nanoparticles and susceptibility to particulate exposure in a murine model of cystic fibrosis

โœ Scribed by Geiser, Marianne; Stoeger, Tobias; Casaulta, Marco; Chen, Shanze; Semmler-Behnke, Manuela; Bolle, Ines; Takenaka, Shinji; Kreyling, Wolfgang G; Schulz, Holger


Book ID
125402202
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
784 KB
Volume
11
Category
Article
ISSN
1743-8977

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Cystic fibrosis (CF) is an inherited disorder associated with severe inflammation and repeated bacterial infection and colonization in the lung. Airway epithelium is involved in defence against bacteria, but this system may be defective in CF. Pro-inflammatory cytokines can stimulate the expression