Bioinspired organic-inorganic composite materials prepared by an alternate soaking process as a tissue reconstitution matrix
✍ Scribed by Ogomi, Daisuke ;Serizawa, Takeshi ;Akashi, Mitsuru
- Book ID
- 102293495
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 199 KB
- Volume
- 67A
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
Abstract
Poly(acrylic acid) (PAAc) grafted poly(ethylene) (PE) (PAAc‐g‐PE) film‐apatite or calcium carbonate (CaCO~3~) composite materials were prepared by an alternate soaking process, which simply forms apatite or CaCO~3~ on the polymer materials by alternate soaking in Ca^2+^‐ and PO‐ or CO~3~^2−^‐containing solutions. X‐ray diffraction analysis of the composite films indicated the presence of hydroxyapatite or CaCO~3~ on the film. Scanning electron microscopic observation revealed that the whole surface of the film was covered by the apatite or CaCO~3~. Cell compatibility tests of the apatite‐ or CaCO~3~‐coated film suggested that the greater number of cells adhered on the films and that the cell proliferation properties were extremely greater on the films. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 67A: 1360–1366, 2003