Bioinformatics: Sequences, Structures, Phylogeny

✍ Scribed by Asheesh Shanker

Publisher: Springer Singapore
Year: 2018
Tongue: English
Leaves: 402
Edition: 1st ed.
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This book provides a comprehensive overview of the concepts and approaches used for sequence, structure, and phylogenetic analysis. Starting with an introduction to the subject and intellectual property protection for bioinformatics, it guides readers through the latest sequencing technologies, sequence analysis, genomic variations, metagenomics, epigenomics, molecular evolution and phylogenetics, structural bioinformatics, protein folding, structure analysis and validation, drug discovery, reverse vaccinology, machine learning, application of R programming in biological data analysis, and the use of Linux in handling large data files.

✦ Table of Contents

Front Matter ....Pages i-ix
Intellectual Property Rights and Bioinformatics: An Introduction ( Shilpa, Umang Gupta)....Pages 1-14
Next-Generation Sequencing: Technology, Advancements, and Applications (Gourja Bansal, Kiran Narta, Manoj Ramesh Teltumbade)....Pages 15-46
Sequence Alignment (Benu Atri, Olivier Lichtarge)....Pages 47-69
Understanding Genomic Variations in the Context of Health and Disease: Annotation, Interpretation, and Challenges (Ankita Narang, Aniket Bhattacharya, Mitali Mukerji, Debasis Dash)....Pages 71-95
Metagenomics: Focusing on the Haystack (Indu Khatri, Meenakshi Anurag)....Pages 97-113
Computational Epigenomics and Its Application in Regulatory Genomics (Shalu Jhanwar)....Pages 115-139
Data Mining to Detect Common, Unique, and Polymorphic Simple Sequence Repeats (Aditi Kapil, C. K. Jha, Asheesh Shanker)....Pages 141-154
R-Programming for Genome-Wide Data Analysis (Arunima Shilpi, Shraddha Dubey)....Pages 155-171
Computational Approaches to Studying Molecular Phylogenetics (Benu Atri, Olivier Lichtarge)....Pages 173-190
Structural Bioinformatics: Life Through The 3D Glasses (Ankita Punetha, Payel Sarkar, Siddharth Nimkar, Himanshu Sharma, Yoganand KNR, Siranjeevi Nagaraj)....Pages 191-253
A Survey of the Structural Parameters Used for Computational Prediction of Protein Folding Process (Gulshan Khalique, Tambi Richa)....Pages 255-270
Quality Assessment of Protein Tertiary Structures: Past, Present, and Future (Ankita Singh, Rahul Kaushik, B. Jayaram)....Pages 271-288
Predicting Protein Function Using Homology-Based Methods (Swati Sinha, Birgit Eisenhaber, Andrew M. Lynn)....Pages 289-305
Drug Discovery: An In Silico Approach (Sukriti Goyal, Salma Jamal, Abhinav Grover, Asheesh Shanker)....Pages 307-328
Advanced In Silico Tools for Designing of Antigenic Epitope as Potential Vaccine Candidates Against Coronavirus (Mehak Dangi, Rinku Kumari, Bharat Singh, Anil Kumar Chhillar)....Pages 329-357
Machine Learning: What, Why, and How? (Salma Jamal, Sukriti Goyal, Abhinav Grover, Asheesh Shanker)....Pages 359-374
Command-Line Tools in Linux for Handling Large Data Files (Deepti Mishra, Garima Khandelwal)....Pages 375-392
Back Matter ....Pages 393-402

✦ Subjects

Life Sciences; Bioinformatics; Computational Biology/Bioinformatics; Computer Appl. in Life Sciences; Protein Structure; Simulation and Modeling

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