Bioinformatics for Evolutionary Biologists: A Problems Approach

✍ Scribed by Bernhard Haubold, Angelika Börsch-Haubold (auth.)

• Publisher: Springer International Publishing
• Year: 2017
• Tongue: English
• Leaves: 321
• Edition: 1
• Category: Library

✦ Synopsis

This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the problems in the same computational environment used for decades in science – the UNIX command line. This is available on all three major operating systems for PCs: Microsoft Windows, Mac-OSX, and Linux. To learn using this powerful system, students analyze sample sequence data by applying generic tools, bioinformatics software, and over 40 programs specifically written for this course. The solutions for all problems are included, making the book ideal for self-study. Problems are grouped into sections headed by an introduction and a list of new concepts and programs. By using practical computing to explore evolutionary concepts and sequence data, the book enables readers to tackle their own computational problems.

✦ Table of Contents

Front Matter ....Pages i-x
The UNIX Command Line (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 1-21
Constructing and Applying Optimal Alignments (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 23-45
Exact Matching (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 47-67
Fast Alignment (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 69-99
Evolution Between Species: Phylogeny (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 101-111
Evolution Within Populations (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 113-126
Additional Topics (Bernhard Haubold, Angelika Börsch-Haubold)....Pages 127-138
Back Matter ....Pages 139-318

✦ Subjects

Bioinformatics