Biogenesis of β-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence

Prediction of membrane spanning segments

Prediction of membrane spanning segments and topology in β-barrel membrane proteins at better accuracy

✍ Yu-yen Ou; Shu-an Chen; M. Michael Gromiha 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 309 KB

## Abstract Prediction of membrane spanning segments in β‐barrel outer membrane proteins (OMP) and their topology is an important problem in structural and functional genomics. In this work, we propose a method based on radial basis networks for predicting the number of β‐strands in OMPs and identi