✦ LIBER ✦

Bioequivalence of carbamazepine chewable and conventional tablets: Single-dose and steady-state studies

✍ Scribed by K. K. H. Chan; R. J. Sawchuk; T. A. Thompson; E. Redalieu; W. E. Wagner Jr.; A. R. Lesher; B. J. Weeks; N. R. Hall; A. Gerardin

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 602 KB
Volume: 74
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600740813

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Prediction of steady-state bioequivalenc

Prediction of steady-state bioequivalence relationships using single dose data I-linear kinetics

✍ André J. Jackson 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 693 KB

Simulated data using a linear one-and two-compartment body model with different absorption characteristics were used to evaluate the ability of single dose bioavailability data to predict the relationships that exist at steady state. This was done by comparing the confidence intervals obtained from

Prediction of steady state bioequivalenc

Prediction of steady state bioequivalence relationships using single dose data II-nonlinear kinetics

✍ André J. Jackson 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 744 KB

Two nonlinear pharmacokinetic models were simulated to investigate the relationship between single and multiple dose bioequivalency parameters for drugs such as phenytoin and propranolol which exhibit either saturable elimination kinetics or a capacity limited first pass effect. Mean T,,,, C, , , an

Multiple-dose pharmacokinetics and bioeq

Multiple-dose pharmacokinetics and bioequivalence of L-carnitine 330-mg tablet versus 1-g chewable tablet versus enteral solution in healthy adult male volunteers

✍ Chandrahas G. Sahajwalla; Edward D. Helton; Edward D. Purich; Charles L. Hoppel; 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 955 KB

Comparative bioavailability and steady s

Comparative bioavailability and steady state fluctuations of tegretol commercial and carbamazepine oros tablets in adult and pediatric epileptic patients

✍ Kamlesh M. Thakker; Surinder Mangat; William R. Garnett; René H. Levy; Gregory M 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB 👁 2 views

## Abstract The comparative bioavailability and steady state fluctuations resulting from the administration of Tegretol 200 mg commercial tablets and carbamazepine OROS controlled delivery tablets were investigated in 22 adult and 12 pediatric epileptic patients. Tegretol commercial tablets were do

Single intravenous dose and steady-state

Single intravenous dose and steady-state oral dose pharmacokinetics of nicardipine in healthy subjects

✍ John G. Wagner; Teck L. Ling; Edward J. Mroszczak; Donna Freedman; Ann Wu; Bee H 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 617 KB

Nicardipine HCI oral doses (10-40 mg) were administered sequentially to six healthy subjects. For each regimen the capsule dose was administered every 8 hours (q 8 h) for 3 days and the plasma profiles of nicardipine and its pyridine analogue (M5) were determined following the last dose on day 4. St

Pharmacokinetic dose-proportionality stu

Pharmacokinetic dose-proportionality study at steady state of mirtazapine from Remeron® tablets

✍ C. J. Timmer; A. A. M. Lohmann; C. P. A. Mink 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 735 KB

Steady-state dose proportionality of mirtazapine, the active constituent of Remeronm tablets, a new antidepressant developed under the laboratory code Org 3770, was investigated. Each of 27 young healthy male subjects received a single daily oral dose of mirtazapine in the form of standard Remeronm