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Bioengineering radioresistance by overproduction of RPA, a mammalian-type single-stranded DNA-binding protein, in a halophilic archaeon

✍ Scribed by Karan, Ram; DasSarma, Priya; Balcer-Kubiczek, Elizabeth; Weng, Rueyhung Roc; Liao, Chen-Chung; Goodlett, David R.; Ng, Wailap Victor; DasSarma, Shiladitya


Book ID
121398845
Publisher
Springer
Year
2013
Tongue
English
Weight
304 KB
Volume
98
Category
Article
ISSN
1432-0614

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## Abstract Single‐stranded guanine‐rich (G‐rich) DNA can fold into a four‐stranded G‐quadruplex structure and such structures are implicated in important biological processes and therapeutic applications. So far, bioinformatic analysis has identified up to several hundred thousand of putative quad