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Bioengineering lysosomal enzymes for travel to the brain

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
62 KB
Volume
99
Category
Article
ISSN
0006-3592

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The turnover rate of an individual protein is a function of the rates of synthesis and loss of that protein. For most intracellular proteins, loss occurs through digestion by lysosomal or cytosolic proteases. Although a significant proportion of hepatic lysosomal enzymes is released from the hepatoc