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Biodistribution of Stealth and Non-stealth Solid Lipid Nanospheres after Intravenous Administration to Rats

โœ Scribed by VALERIO PODIO; GIAN PAOLO ZARA; MARILENA CARAZZONE; ROBERTA CAVALLI; MARIA ROSA GASCO

Book ID
111768547
Publisher
Pharmaceutical Press
Year
2000
Tongue
English
Weight
115 KB
Volume
52
Category
Article
ISSN
2042-7158

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Pharmacokinetics and tissue distribution of idarubicin-loaded solid lipid nanoparticles after duodenal administration to rats
โœ Zara, Gian Paolo (author);Bargoni, Alessandro (author);Cavalli, Roberta (author) ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 143 KB

Idarubicin-loaded solid lipid nanoparticles (IDA-SLN) and idarubicin in solution were prepared and the two formulations were administered to rats, either by the duodenal route or intravenously (iv). The aim of this research was to study whether the bioavailability of idarubicin can be improved by ad