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Biodistribution and hepatic uptake of a 111In-labelled monoclonal antibody in the rat

✍ Scribed by C.C. Boyle; S.J. Mather; A.J. Paine

Book ID: 115884561
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 191 KB
Volume: 183
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(90)92725-x

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## Abstract Clinical and experimental scintigraphic studies have found that radiolabelled antibodies are not only taken up by tumour (s) but also by normal liver. The accumulation of radio nuclides in this organ poses a major problem to the use of radiolabelled antibodies as diagnostic and therapeu