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Biodistribution and brain permeability of the extracellular domain of neuregulin-1-β1

✍ Scribed by Thomas W. Rösler; Candan Depboylu; Oscar Arias-Carrión; Wojciech Wozny; Thomas Carlsson; Matthias Höllerhage; Wolfgang H. Oertel; André Schrattenholz; Günter U. Höglinger

Book ID
116785821
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
762 KB
Volume
61
Category
Article
ISSN
0028-3908

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Fmoc-based solid phase chemical synthesi
Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-β1, an epidermal growth factor-like domain
✍ Taeko Kakizawa; Shizuyo Koide-Yoshida; Tooru Kimura; Hiromasa Uchimura; Yoshio H 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

## Abstract The human neuregulin 1‐β1 (NRG1‐β1, amino acid residues 176–246) was chemically synthesized by Fmoc‐based solid phase peptide synthesis (SPPS) followed by folding in a redox buffer. The biological activity of the synthesized NRG1‐β1 was confirmed by ligand‐induced tyrosine phosphorylati