The in vitro metabolism and bioactivatio
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Wiersma, David A. ;Schnellmann, Rick G. ;Sipes, I. Glenn
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Article
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1986
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John Wiley and Sons
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English
⚖ 610 KB
The nematocide, grain fumigant, and gasoline additive 1,2-dibromoethane (DBE) is both a cellular and a genetic toxin that is metabolically activated in rats and mice by mixed function oxidases (MFO) as well as glutathione S-transferases (GST). The purpose of this study was to determine whether DBE i