Biodegradable thermogelling poly(ester urethane)s consisting of poly(lactic acid) – Thermodynamics of micellization and hydrolytic degradation
✍ Scribed by Xian Jun Loh; Yun Xuan Tan; Ziyun Li; Lin Shin Teo; Suat Hong Goh; Jun Li
- Book ID
- 108069885
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 756 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0142-9612
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The hydrolysis behaviour of lactic acid based poly(ester-urethane)s has been studied in a bu †er solution of pH 7É00 at 37 and 55¡C. Samples were prepared using a straight two step lactic acid polymerization process. The lactic acid was Ðrst polymerized by condensation with a low molecular weight by
Biodegradable PHB-PEG multi-block polyurethane copolymers comprising PHB blocks (M n : 1100, 1740 and 3240) and PEG blocks (M n : 1960, 3250, 4150 or 7950) were synthesized followed by characterization by GPC, 1 H NMR, and FT-IR. The PHB contents ranged from 9 to 62% by weight. The copolymers displa