Biodegradable radioactive implants for glaucoma filtering surgery produced by ion implantation

✍ Scribed by W. Assmann; M. Schubert; A. Held; A. Pichler; A. Chill; S. Kiermaier; K. Schlösser; H. Busch; K. Schenk; D. Streufert; I. Lanzl

• Book ID: 103861774
• Publisher: Elsevier Science
• Year: 2007
• Tongue: English
• Weight: 480 KB
• Volume: 257
• Category: Article
• ISSN: 0168-583X
• DOI: 10.1016/j.nimb.2006.12.155

✦ Synopsis

A biodegradable, b-emitting implant has been developed and successfully tested which prevents fresh intraocular pressure increase after glaucoma filtering surgery. Ion implantation has been used to load the polymeric implants with the b-emitter 32 P. The influence of ion implantation and gamma sterilisation on degradation and 32 P-fixation behavior has been studied by ion beam and chemical analysis. Irradiation effects due to the applied ion fluence (10 15 ions/cm 2 ) and gamma dose (25 kGy) are found to be tolerable.