Biodegradable Polymers in Clinical Use and Clinical Development

✍ Scribed by Abraham J. Domb, Neeraj Kumar

• Publisher: Wiley
• Year: 2011
• Tongue: English
• Leaves: 752
• Edition: 1
• Category: Library

✦ Synopsis

This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development.The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

✦ Table of Contents

Biodegradable Polymers in Clinical Use and Clinical Development......Page 5
Contents......Page 7
Contributors......Page 11
Preface......Page 15
Part I: General......Page 19
1: Biodegradable Polymers in Drug Delivery: Jay Prakash Jain, Wubante Yenet, Abraham J. Domb, and Neeraj Kumar......Page 21
Part II: Biodegradable Polymers of Natural Origin: Protein-Based Polymers......Page 77
2: Collagen: Wahid Khan, Deepak Yadav, Abraham J. Domb, and Neeraj Kumar......Page 79
3: Properties and Hemostatic Application of Gelatin: Jalindar Totre, Diana Ickowicz, and Abraham J. Domb......Page 109
Part III: Biodegradable Polymers of Natural Origin: Polysaccharides......Page 129
4: Chitosan and Its Derivatives in Clinical Use and Applications: Anuradha Subramanian, Kirthanashri Srinivasan Vasanthan,Uma Maheswari Krishnan, and Swaminathan Sethuraman......Page 131
5: Clinical Uses of Alginate: Udi Nussinovitch and Amos Nussinovitch......Page 155
6: Dextran and Pentosan Sulfate — Clinical Applications: Ramu Parthasarathi and Athipettah Jayakrishnan......Page 203
7: Arabinogalactan in Clinical Use: Rajendra P. Pawar, Babasaheb A. Kushekar, Bhaskar S. Jadhav, Kiran R. Kharat, Ravikumar M. Borade, and Abraham J. Domb......Page 235
Part IV: Biodegradable Polymers of Natural Origin: Polyesters......Page 265
8: Polyhydroxyalkanoate: Kesaven Bhubalan, Wing-Hin Lee, and Kumar Sudesh......Page 267
Part V: Synthetic Biodegradable Polymers......Page 335
9: Lactide and Glycolide Polymers: Kevin Letchford, Anders Södergard, David Plackett, Samuel Gilchrist, and Helen Burt......Page 337
10: Polyanhydrides-Poly(CPP-SA), Fatty-Acid-Based Polyanhydrides: Ravikumar M. Borade, Abraham J. Domb, Archana A. Sawale, Rajendra P. Pawar, and Kiran R. Kharat......Page 385
11: Poly(&03B5;-Caprolactone-co-Glycolide): Biomedical Applications of a Unique Elastomer: Kevin Cooper, Aruna Nathan, and Murty Vyakarnam......Page 419
12: Medicinal Applications of Cyanoacrylate: Rajendra P. Pawar, Ashok E. Jadhav, Sumangala B. Tathe, Bhimrao C. Khade, and Abraham J. Domb......Page 435
13: Polyethylene Glycol in Clinical Application and PEGylated Drugs: Teerapol Srichana, and Tan Suwandecha......Page 469
Part VI: Inorganic Polymers......Page 513
14: Calcium-Phosphate-Based Ceramics for Biomedical Applications: Qing Lv, Kevin W.-H. Lo, Lakshmi S. Nair, and Cato T. Laurencin......Page 515
Part VII: Biodegradable Polymers for Emerging Clinical Uses......Page 537
15: Biocompatible Polymers for Nucleic Acid Delivery: Jeff Sparks, and Khursheed Anwer......Page 539
16: Biodegradable Polymers for Emerging Clinical Use in Tissue Engineering: Shalini Verma, Kalpna Garkhal, Anupama Mittal, and Neeraj Kumar......Page 583
17: Injectable Polymers: Shimon A. Unterman, Norman A. Marcus, and Jennifer H. Elisseeff......Page 649
Part VIII: IPR Aspects of Biodegradable Polymers......Page 683
18: Global Patent and Technological Status of Biodegradable Polymers in Drug Delivery and Tissue Engineering: Parikshit Bansal, Shalini Verma, Wahid Khan, and Neeraj Kumar......Page 685
Index......Page 745