✦ LIBER ✦

Biodegradable Polymeric Nanoparticles as Templates for Biomimetic Mineralization of Calcium Phosphate

✍ Scribed by Anitha Ethirajan; Anna Musyanovych; Andrey Chuvilin; Katharina Landfester

Book ID: 102939457
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 957 KB
Volume: 212
Category: Article
ISSN: 1022-1352
DOI: 10.1002/macp.201000694

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✦ Synopsis

Abstract

Biodegradable polymeric nanoparticles are employed as templates for the biomimetic mineralization of CaP in the aqueous phase. Particles in the sub‐µm range were prepared by a combination of solvent evaporation and miniemulsion techniques. The synthesized particles were subjected to degradation via random saponification. The anionic functional groups produced as a consequence of degradation due to production (ultrasonication step) and post treatment (hydrolysis) steps are used for the CaP mineralization. The composite particles were studied using HRSEM, TEM, and XRD. These polymer/CaP composite nanoparticles have a great potential to be used as a regenerative filler or as a scaffold for nucleation and growth of new bone material.
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