Biodegradable polymer film reinforcement of an indocyanine green-doped liquid albumin solder for laser-assisted incision closure
✍ Scribed by Brian S. Sorg; Karen M. McNally; Ashley J. Welch
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 688 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
✦ Synopsis
Background and objective:
The purpose of this study was to determine whether solid material reinforcement of a liquid albumin solder coagulum could improve the cohesive strength of the solder and, thus, the ultimate breaking strength of the incision repair in vitro.
Study design/materials and methods:
A 50%(w/v) bovine serum albumin solder with 0.5 or 2.5 mg/ml indocyanine green (icg) dye was used to repair an incision in bovine aorta. the solder was coagulated with an 806-nm continuous wave diode laser. a 50-micrometer-thick poly(dl-lactic-co-glycolic acid) film was used to reinforce the solder (the controls had solder but no reinforcement). acute breaking strengths were measured, and the data were analyzed by student's t-test.
Results:
Observations of the failure modes indicate cohesive strength reinforcement of the test specimens vs. the controls. the 2.5 mg/ml icg reinforced solder was stronger than the controls without reinforcement (p < 0.05) for all laser powers tested. there was no difference between the test specimens and the controls with 0.5 mg/ml icg solder for low laser powers, but at higher laser powers, the reinforced solder was stronger than the controls (p < 0.05).
Conclusion:
Reinforcement of liquid albumin solders in laser-assisted incision repair seems to have advantages in terms of acute breaking strength over conventional methods that do not reinforce the cohesive strength of the solder.