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Biodegradable pH-Dependent Thermo-Sensitive Hydrogels for Oral Insulin Delivery

✍ Scribed by Zhe Zhang; Xiaoye Gao; Aiping Zhang; Xiaowei Wu; Li Chen; Chaoliang He; Xiuli Zhuang; Xuesi Chen

Book ID
112141275
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
515 KB
Volume
213
Category
Article
ISSN
1022-1352

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Using pH-sensitive hydrogels containing
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## Abstract The goal of oral insulin delivery devices is to protect the sensitive drug from proteolytic degradation in the stomach and upper portion of the small intestine. Copolymers of 2‐hydroxyethyl methacrylate (HEMA) and methacrylic acid (MAA) based hydrogels containing 2, 4, and 6% of a cross