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Biodegradable Elastomers for Tissue Engineering and Cell–Biomaterial Interactions

✍ Scribed by Christopher J. Bettinger

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
775 KB
Volume
11
Category
Article
ISSN
1616-5187

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✦ Synopsis

Abstract

Synthetic biomaterials serve as a cornerstone in the development of clinically focused regenerative medicine therapies that aim to reduce suffering and prolong life. Recent improvements in biodegradable elastomeric materials utilize natural extracellular matrix proteins as inspiration to yield a new class of materials with superior degradation kinetics, desirable biocompatibility profiles, and mechanical properties that closely match those of soft tissues. This review describes several classes of synthetic biodegradable elastomers and associated fabrication techniques that are relevant to scaffold development. The application of these materials to select tissue engineering models is also discussed. magnified image

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