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Biodegradability of sol–gel silica microparticles for drug delivery

✍ Scribed by Kim S. Finnie; Daniel J. Waller; Francois L. Perret; Anwen M. Krause-Heuer; Hui Q. Lin; John V. Hanna; Christophe J. Barbé

Publisher
Springer
Year
2008
Tongue
English
Weight
323 KB
Volume
49
Category
Article
ISSN
0928-0707

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Sol-gel-processed sintered silica xerogel as a carrier in controlled drug delivery
✍ Kortesuo, Pirjo ;Ahola, Manja ;Karlsson, Stefan ;Kangasniemi, Ilkka ;Kiesvaara, 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB 👁 2 views

Sol-gel-processed sintered silica xerogel was studied as a controllable, dissolvable, implantable material. The erosion of the matrix and the release of the preadsorbed drug toremifene citrate was investigated both in vitro and in vivo using mice. In an in vitro dissolution study, 50 to 60% of the d