Biodefense : research methodology and animal models

✍ Scribed by Swearengen, James R

Publisher: Taylor & Francis
Year: 2012
Tongue: English
Leaves: 415
Edition: 2nd ed
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum Read more...

Abstract: Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed in this volume include: A history of biological agents as weapons, from the use o

✦ Table of Contents

Content: History of biological agents as weapons / James W. Martin --
Bioterrorism and biowarfare : similarities and differences / Nelson W. Rebert --
Scientific and ethical importance of animal models in biodefense research / James R. Swearengen and Arthur O. Anderson --
Development and validation of animal models / Jaime B. Anderson and Kenneth Tucker --
Infectious disease aerobiology : aerosol challenge methods / Chad J. Roy and Louise M. Pitt --
Characterization of new and advancement of existing animal models of bacillus anthracis infection / Elizabeth K. Leffel and Louise M. Pitt --
Glanders / David L. Fritz and David M. Waag --
Plague / Jeffery J. Adamovicz and Patricia L. Worsham --
Tularemia / Jeffery J. Adamovicz and David M. Waag --
Q fever / David M. Waag and David L. Fritz --
Brucellosis / Bret K. Purcell and Robert Rivard --
Alphaviruses / William D. Pratt [and others] --
Orthopoxviruses / Peter B. Jahrling and Victoria Wahl-Jensen --
Animal models for viral hemorrhagic fevers / Kelly l. Warfield and Thomas W. Geisbert --
Botulinum toxins / Stephen B. Greenbaum, Jaime B. Anderson, and Frank J. Lebeda --
Ricin / Stephen B. Greenbaum and Jaime B. Anderson --
Staphylococcal and streptococcal superantigens : in vitro and in vivo assays / Teresa Krakauer and Bradley G. Stiles.

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