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Bioconversions in an aqueous two-phase system using enzymes immobilized on ultrafine silica particles

✍ Scribed by Akihiko Kondo; Takafumi Urabe; Ko Higashitani


Book ID
113397288
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
379 KB
Volume
77
Category
Article
ISSN
0922-338X

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Yields of kinetically controlled synthesis of antibiotics catalyzed by penicillin G acylase from Escherichia coli (PGA) have been greatly increased by con- tinuous extraction of water soluble products (cephalexin) away from the surroundings of the enzyme. In this way its very rapid enzymatic hydroly