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Bioconversion of 3-chlorobenzoate to 2-chloromuconate controlled by on line HPLC

✍ Scribed by Eberhard Schmidt


Publisher
Springer
Year
1988
Tongue
English
Weight
340 KB
Volume
27
Category
Article
ISSN
1432-0614

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Decomposition of 3′-azido-2′,3′-dideoxyt
✍ Isabelle Lefebvre; Thierry Beltran; Suzanne Peyrottes; Christian Périgaud 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB 👁 2 views

## Abstract Using a column‐switching HPLC method previously described, we studied the behavior of some mononucleotide prodrugs (pronucleotides) of 3′‐azido‐2′,3′‐dideoxythymidine in various biological media. From UV data, this method allowed quantification of transient metabolites resulting from pr