Biocompatibility study of hydroxyapatite-chitosan composite for medical applications at microwave frequencies

✍ Scribed by Robin Augustine; Ullas G. Kalappura; K. T. Mathew

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 299 KB
• Volume: 50
• Category: Article
• ISSN: 0895-2477
• DOI: 10.1002/mop.23806

✦ Synopsis

Abstract

Hydroxyapatite (HAp, Ca10(PO~4~)~6~(OH)~2~) bioceramic and chitosan (poly [(β‐1‐4) D‐glucosamine]) biopolymer show good biocompatibility in vivo. They have biological origin and show excellent interactions with microwave. Microwave study of HAp made using different drying techniques and their composites with chitosan in the ISM band is presented. Pastes are made using HAp and chitosan with different ratios of mixing. The dielectric properties of this composites match with that of human fat, collagen tissues. Some of the compositions exhibit dielectric property close to that of natural bone. This makes them more biocompatible and better substitutes for natural bone. Thus composite bioceramics can be considered as phantom model constituents for imaging purposes. Their dielectric properties prove that they are biocompatible. © 2008 Wiley Periodicals, Inc. Microwave Opt Technol Lett 50: 2931–2934, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.23806