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Biocompatibility studies on surgical-grade titanium-, cobalt-, and iron-base alloys

✍ Scribed by Lemons, J. E. ;Niemann, K. M. W. ;Weiss, A. B.

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
252 KB
Volume
10
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

An animal model system for the investigation of the influence of in vivo‐ produced metallic corrosion products upon tissues has been developed. Externally applied electrical stimulation produces the corrosion over a short period of time, and a poststimulation period is allowed for tissue stabilization.

Tissue reaction adjacent to the metallic alloys shows fibrous tissue capsules and metallic corrosion product contamination.

These preliminary studies show that this animal model and methodology may provide a technique for investigating long‐term tissue biomaterial interactions and the influence of iron (316L), cobalt (Vitallium), and titanium (Tivanium) alloy corrosion products upon the susceptibility of tissues to various biocompatibility challenges.

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