Biocompatibility of nickel-titanium shape memory metal and its corrosion behavior in human cell cultures

✍ Scribed by Ryh�nen, J. ;Niemi, E. ;Serlo, W. ;Niemel�, E. ;Sandvik, P. ;Pernu, H. ;Salo, T.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 187 KB
• Volume: 35
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/(sici)1097-4636(19970615)35:4<451::aid-jbm5>3.0.co;2-g

✦ Synopsis

Nickel-titanium alloy (Nitinol) is a metallic bio-control cultures. The proliferation of OB was 101% (Nitinol), material that has a unique thermal shape memory, superelas-100% (Ti), 105% (Stst), and 54% (C) (p Ͻ 0.025) compared to ticity, and high damping properties. Nitinol is potentially the controls. Initially, Nitinol released more nickel (129-87 very useful in orthopedic surgery, for example. At present, g/L) into the cell culture media than Stst (7 g/L), but there are not enough confirmative biocompatibility data after 2 days the concentrations were about equal (23-5 g/L available on Nitinol. The aim of our study was to clarify the versus 11-1 g/L). The titanium concentrations from both primary cytotoxicity and corrosion rate of Nitinol in human Nitinol and Ti samples were all Ͻ20 g/L. We conclude cell cultures. Comparisons were made with stainless steel that Nitinol has good in vitro biocompatibility with human (Stst), titanium (Ti), composite material (C), and control cul-osteoblasts and fibroblasts. Despite the higher initial nickel tures with no test discs. Human osteoblasts (OB) and fibro-dissolution, Nitinol induced no toxic effects, decrease in cell blasts (FB) were incubated for 10 days with test discs of equal proliferation, or inhibition on the growth of cells in contact size, 6 ϫ 7 mm. The cultures were photographed and the with the metal surface.