Biochemistry of the sterol group

✍ Scribed by Butenandt, A.

• Book ID: 102886550
• Publisher: Wiley (John Wiley & Sons)
• Year: 1936
• Weight: 543 KB
• Volume: 55
• Category: Article
• ISSN: 0368-4075
• DOI: 10.1002/jctb.5000554002

✦ Synopsis

Hygiene and Tropical Medicine on

May 5, 7 ,

and

8, 1936)

(I). THE STEROLS

T h sterols arc \ ~l l l<n0\.11 totliiy ils spccial class of substrinccs occurring in orgtiuisms side by side with the fats, cnrboliydrntes, protcins, iintl nuclcoprotcins. !I'licy scciii to bc priinnry cell coiistitucnts of all plant nnd nniiiinl cclls and nppnrcntly arc missing only froiii hnctcria.* 'J'hc stcrols arc unscituratcd nlcohols of liigli 1nolccdiir wciglit which arc clcissificd according to tlicir origiii, as, nniiiinl sterols (zoostcrols), plant sterols (phytostcrols), nnil fungus sterols (inycostcrols). licccnt,ly, it lins bccii shown that all sterols tire vcry siiirilnr in t l d r constitution rind nrc dcrivntivcs of OIIC nntl tJa snnic funtln~i~cntal skclcton. Tiiis cnr11011 skclctoii is tlic c~~clo~~c~~tii~io~~erl~ytlro~~lic~~:~~itlirc~ic of forriiuln I. L l I -( C l ~, ) , -~f l CH, (< 1.1, C1-l3 110 cllolcslol~ol U,,I.IOO Tlic bcst kuowii fiiugus sterol is crgostcrol C2,Ti,l,0 aid tlic most fully in\wtigntcd plnnt sterol is stigmiistcrol C!2011,180. Poi*niulm 1 I1 tint1 IV slio\v tlint crgostcrol contains ti nictliyl group iind two iloublc * llccuntly SilIurd iiritl Autlurscin l i i i w ~I ~I ~W I I t h i i L .4:ololucler chroocoectitir prubiilly rontiiilin sterols. (X. phyaiol. Cltctn,, 1930, 239, 270).