✦ LIBER ✦

Biochemistry of selective toxicity and biodegradability—II. Comparative in vivo and microsomal O-dealkylation by mice and flies

✍ Scribed by Larry G. Hansen; Robert L. Metcalf; Inder P. Kapoor

Book ID: 119534123
Publisher: Elsevier Science
Year: 1974
Weight: 413 KB
Volume: 5
Category: Article
ISSN: 0010-4035
DOI: 10.1016/s0306-3623(74)80021-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Biochemistry of selective toxicity and b

Biochemistry of selective toxicity and biodegradability: Comparative O-dealkylation by aquatic organisms

✍ Larry G. Hansen; Inder P. Kapoor; Robert L. Metcalf 📂 Article 📅 1972 🏛 Elsevier Science ⚖ 436 KB

Metabolism of the mesoionic compound (MI

Metabolism of the mesoionic compound (MI-D) by mouse liver microsome, detection of its metabolite In Vivo, and acute toxicity in mice

✍ Silvia Romão; Silvia M. S. C. Cadena; Juliana C. Amorim; Stelia C. Méndez-Sánche 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 528 KB

## Abstract The mesoionic derivative 4‐phenyl‐5‐[4‐nitrocinnamoyl]‐1,3,4‐thiadiazolyl‐2‐phenylamine chloride (MI‐D) has antitumoral and anti‐inflammatory effects. In this study, we present aspects of its metabolism and toxicity in mice. MI‐D was metabolized __in vitro__ by liver microsome, generati