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Biochemical studies on pigment granules in the liver of dubin-johnson syndrome

โœ Scribed by Takino, T. ;Nonomura, Y. ;Masuda, M. ;Takino, S.

Publisher
Springer-Verlag
Year
1971
Tongue
English
Weight
276 KB
Volume
6
Category
Article
ISSN
0435-1339

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โœ Tsuneo Kitamura; Joseph Alroy; Zenaida Gatmaitan; Masayasu Inoue; Takashi Mikami ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 853 KB

Dubin-Johnson patients, mutant Corriedale sheep and TRand EHBR mutant rats have recessively inherited defective bile canalicular secretion of many nonbile acid organic anions. The human and ovine mutants have black livers and lysosomal pigment accumulation. The livers in TR-and EHBR mutant rats are