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Biochemical studies of methotrexate resistance in choriocarcinoma of the human placenta and testis

โœ Scribed by Joseph Jarabak; Nicholas R. Bachur


Book ID
115766047
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
343 KB
Volume
5
Category
Article
ISSN
0006-2944

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Methotrexate-induced resistance to dacti
โœ Setsuko Goto; Yoshie Okayama; Bachelor Of Agriculture; Chen Fan; Shiomi Ueda; Ba ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 458 KB

NaUCC-2, a choriocarcinoma cell line, was derived from a patient who had a very poor clinical response to combination chemotherapy. Methotrexate (MTX) might have inhibited the antitumor effect of dactinomycin. To investigate this point, in vitro studies were performed to determine the sensitivity an