Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation

Aminopeptidase Inhibitory Properties and

Aminopeptidase Inhibitory Properties and Analgesic Activity of (2S,3,7-3,7-Diamino-2-hydroxy-heptanoic Acid Containing Tripeptide Analogues of the N-Terminal Tripeptide of Probestin

✍ Rosario Herranz; Soledad Vinuesa; Concepción Pérez; M. Teresa García-López; Marí 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 2 views

2S,3R)-3,7-Diamino-2-hydroxy-heptanoyl-Leu-h-OH [(=.3R)-DAHHA-Leu-Pro-OH, 41. analogue of the N-terminal hipeptide of probatin, has been synthesized, and tested as inhibitor of AP-B, Leu-AP, AP-M, and enkephalindegrading A h , and as analgesic. In order to establish structure-activity relationships