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Biochemical Mechanisms of Induction of Hepatic Peroxisome Proliferation

โœ Scribed by Lock, E A; Mitchell, A M; Elcombe, C R

Book ID
115499554
Publisher
Annual Reviews
Year
1989
Tongue
English
Weight
725 KB
Volume
29
Category
Article
ISSN
0362-1642

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Species differences in ciprofibrate indu
Species differences in ciprofibrate induction of hepatic cytochrome p450 4A1 and peroxisome proliferation
โœ Makowska, Janet M. ;Gibson, G. Gordon ;Banner, Frank W. ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 849 KB

Six species (CD-1 mouse, Fischer 344 rat, Syrian golden hamster, Duncan-Hartley guinea pig, half-lop rabbit and marmoset monkey) were treated orally with ciprofibrate, a potent oxyisobutyrate hypolipidaemic drug for 14 days. A dosedependent liver enlargement was observed in the mouse and rat and at