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Biochemical Mechanisms of IL-2–Regulated Fas-Mediated T Cell Apoptosis

✍ Scribed by Yosef Refaeli; Luk Van Parijs; Cheryl A London; Jürg Tschopp; Abul K Abbas

Book ID
117722909
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
318 KB
Volume
8
Category
Article
ISSN
1074-7613

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## Thiols prevent Fas (CD95)-mediated T cell apoptosis by down-regulating membrane Fas expression Thiol antioxidants have been shown to protect cells against apoptosis. Based on the role of Fas in T cell apoptosis, we investigated the effect of thiols on Fas expression. We report that the thiol N-