✦ LIBER ✦

Biochemical mechanisms for the scheduled synergism of (αS, 5S)-2 amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid and 5-fluorouracil in P388 leukemia

✍ Scribed by Bach Ardalan; Bangaru Chandrasekaran; H. J. Hrishikeshavan

Book ID: 104687103
Publisher: Springer
Year: 1985
Tongue: English
Weight: 505 KB
Volume: 15
Category: Article
ISSN: 0344-5704
DOI: 10.1007/bf00257293

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Additions and Corrections - Total Synthe

Additions and Corrections - Total Synthesis of Antitumor Agent AT-125(αS,5S)-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic Acid

✍ Baldwin, Jack; Kruse, Lawrence; Cha, Jin-Kun 📂 Article 📅 1982 🏛 American Chemical Society 🌐 English ⚖ 94 KB

The binding mechanism of glutathione and

The binding mechanism of glutathione and the anti-tumor drug L-(αS.5S)-α-amino-3-chloro-4.5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501) to γ-glutamyltransferase

✍ Charles S. Schasteen; Norman P. Curthoys; Donald J. Reed 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 343 KB

Stereospecific total syntheses of the na

Stereospecific total syntheses of the natural antitumor agent, (.alpha.S, 5S)-.alpha.-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, and its unnatural C-5 epimer

✍ Silverman, Richard B.; Holladay, Mark W. 📂 Article 📅 1981 🏛 American Chemical Society 🌐 English ⚖ 298 KB

Interaction of the antitumor drug, L-(αS

Interaction of the antitumor drug, L-(αS, 5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) with renal brush border membranes: Specific labeling of γ-glutamyl transpeptidase

✍ Elena M. Kozak; Suresh S. Tate 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 487 KB

The inhibition of γ-glutamyl transpeptid

The inhibition of γ-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(αS, 5S)-α-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501)

✍ Donald J. Reed; William W. Ellis; Robert A. Meck 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 268 KB

Preparation of a new chiral stationary p

Preparation of a new chiral stationary phase for HPLC based on the (R)- 1-phenyl-2-(4-methylphenyl)ethylamine amide derivative of (S)-valine and 2-chloro-3,5-dinitrobenzoic acid: Enantioseparation of amino acid derivatives and pyrethroid insecticides

✍ Xulin Tan; Shicong Hou; Jingli Jiang; Min Wang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB 👁 1 views

## Abstract A novel chiral stationary phase (CSP) for HPLC was prepared by bonding (__R__)‐1‐phenyl‐2‐(4‐methylphenyl)ethylamine amide derivative of (__S__)‐valine to aminopropyl silica gel through a 2‐amino‐3,5‐dinitro‐1‐carboxamido‐benzene unit. The CSP was used for the separation of some amino a