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Biochemical evidence that the N-terminal segments of the α subunit and the β subunit play interchangeable roles in the activation of protein kinase CK2

✍ Scribed by Stefania Sarno; Oriano Marin; Paola Ghisellini; Flavio Meggio; Lorenzo A Pinna

Book ID: 117110130
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 184 KB
Volume: 441
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(98)01516-6

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## Abstract A novel mutant of the catalytic α subunit of human protein kinase CK2 (CK2α) was designed in an attempt to clarify the role of the carboxylic‐terminal segment characteristic of vertebrates, excluding fish. Starting from the sequence alignments, we constructed a phylogenetic tree of the