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Biochemical Evidence for Induction by Polyoma Virus of Replication of the Chromosomes of Mouse Kidney Cells

✍ Scribed by R. Hancock and R. Weil

Book ID
123649141
Publisher
National Academy of Sciences
Year
1969
Tongue
English
Weight
905 KB
Volume
63
Category
Article
ISSN
0027-8424

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## Abstract Viral transformation models may be useful to detect and map human tumor suppressor genes. BK virus (BKV), a human papovavirus, readily transforms rodent cells but is unable to transform human cells, suggesting that oncosuppressive functions expressed in human cells control BKV oncogenic