Effect of allopurinol on the toxicity of
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Stephen B. Howell; Craig E. Pfeifle; Wally E. Wung
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Article
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1983
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John Wiley and Sons
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English
β 555 KB
The effect of allopurinol pretreatment on the toxicity of 5-tluorouracil(5-FU) was examined in a clinical trial. Twenty-three patients were given bolus infusions of 5-FU every two weeks in doses that produced mild toxicity (0.8-1 .9 g/m'). O n alternate courses patients were pretreated with allopuri