Characterization and regulation of insul
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Alessandra Gentilini; Denis Feliers; Massimo Pinzani; Kathleen Woodruff; Sherry
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Article
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1998
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John Wiley and Sons
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English
โ 376 KB
๐ 2 views
Cultured hepatic stellate cells (HSCs), the cell type primarily involved in the progression of liver fibrosis, secrete insulin-like growth factor-I (IGF-I) and IGF binding protein (IGFBP) activity. IGF-I exerts a mitogenic effect on HSCs, thus potentially contributing to the fibrogenic process in an