Co-localization of the channel activatin
✍
Karin List; John P. Hobson; Alfredo Molinolo; Thomas H. Bugge
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 677 KB
## Abstract Prostasin (CAP1/PRSS8) is a glycosylphosphatidylinositol‐anchored membrane serine protease believed to be critical for the regulation of epithelial sodium channel (ENaC) activity. Prostasin is synthesized as an inactive zymogen that requires a site‐specific endoproteolytic cleavage to b