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Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion

✍ Scribed by Gloria Gallo; Thiago Cesar Prata Ramos; Fernanda Tavares; Antonio A. Rocha; Emerson Machi; Sergio Schenkman; Diana Bahia; João Bosco Pesquero; Martin Würtele

Book ID: 116301680
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 376 KB
Volume: 408
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2011.04.038

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As in other fields of biomedical research, the use of gene-targeted mice by homologous recombination in embryonic stem cells has provided important findings on the function of several members of the protein tyrosine phosphatase (PTP) family. For instance, the phenotypic characterization of knockout