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Biochemical characterization of a factor released by macrophages

✍ Scribed by Hans-G. Opitz; Dietrich Niethammer; Robert C. Jackson; Hilmar Lemke; Richard Huget; Hans-D. Flad

Book ID
115810666
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
370 KB
Volume
18
Category
Article
ISSN
0008-8749

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A deactivating factor (MDF) is released from granuloma-like lesions of mice (giant and epithelioid macrophages) to the surrounding medium. Test cells incubated in the presence of MDF display dramatic inhibition of superoxide anion ((I2-) release when stimulated. This failure to manifest 0, release i